Citicoline

Citicoline is a naturally occurring compound found in the body and an integral building block of cell membranes. It is meant to increase the level of phosphatidylcholine, a chemical necessary for brain function, and can be effective in treating problems related to memory and cognition. It is typically prescribed in Europe and Japan as a way of improving the memory, thinking, and brain function of people recovering from a stroke and can be taken either as an oral supplement or as an injection. It is notable for providing both neuroprotection and enhanced neurorepair with fewer side effects than other tested agents and methods, and can offer long-term beneficial effects in post-stroke patients.

Studies into the potential use of citicoline as a viable method of treating Alzheimer’s disease, Parkinson’s disease, glaucoma, and bipolar disorder are ongoing.

Citicoline is usually sold in 250-mg, 300-mg, 500-mg, and 1,000-mg capsules or tablets.

Administered dosage to be taken by mouth:

• Decline in memory and thinking skills due to age: between 1 and 2-grams daily.
• Eye disorders that can lead to vision loss (glaucoma): between 500 and 1,600-milligrams daily.
• Stroke: between 500 and 2,000-milligrams daily.

Citicoline can also be administered by injection via a healthcare provider either as a shot into the muscle to treat glaucoma or into the vein (IV) to treat problems related to memory and thinking skills due to aging and can help improve recovery after a stroke.

Adverse effects as a result of taking citicoline are rare or minor, but can include stomach pain and/or diarrhea.

While there has been little information about the use of citicoline in pregnant or nursing women, it is best to be cautious and avoid use.

Citicoline should be safe for oral use in children aged 1-13 years.